Your IA is correct. You can choose to opt to fly with the pressurization inop. Just like you can choose to fly with it turned off (there is an on/off switch).
You cannot remove the system in however -which I think you mean as de-rating- as the pressurization system is linked and a part of other systems such as heating (combustion heater) and ventilation. By opting to fly with the pressurization inop, you end up carrying the weight of the system for no benefit.
As mentioned somewhere else though, the pressurization system has proven reliable for me. As have the turbos.
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